PreonUnlocks: Automation, Catastrophe, and EntropyUnlock by accumulating score.
ScribblesUnlocks: Intimidating Helmet, Reptile Trinket, and Unsettling LampUnlock by accumulating score.
The ArchitectUnlocks: Eternal Armor, Jackpot, and Prep TimeUnlock by accumulating score.
NemesisUnlocks: Helical Dart, Snecko Skull, and Twisted FunnelKill 15 Bosses with the Silent to reveal this Epoch.
SeedsUnlocked game mode: Custom.Beat Act 3 three times to reveal this Epoch.
ElsewhereIt is not yet known what this unlocked...Unlock by accumulating score.
AncientsUnlocks: Book of Five Rings, Ice Cream, and KusarigamaUnlock by accumulating score.
TraitorsUnlocks: Beat Down, Prowess, and RendUnlock by accumulating score.
The PactUnlocks: Ashwater, Blood Potion, Soldier's Stew, and AscensionBeat Act 3 with the Ironclad to reveal this Epoch.
DevastationUnlocks: Paper Phrog, Red Skull, and Ruined HelmetBeat Act 2 with the Ironclad to reveal this Epoch.
SomewhereIt is not yet known what this unlocked...Unlock by accumulating score.
SlumberUnlocks: Alchemize, Nostalgia, and ScrawlUnlock by accumulating score.
ConsequencesUnlocks: Miniature Cannon, Tungsten Rod, and White StarUnlock by accumulating score.
The SpireUnlocks: Colorful PhilosophersUnlock by accumulating score.
The IroncladUnlocks: Cruelty, Dominate, and Molten FistBeat Act 1 with the Ironclad to reveal this Epoch.
Buy Something!Unlocks: Anointed, Calamity, and SplashUnlock by accumulating score.
TrophiesUnlocks: Cunning Potion, Ghost in a Jar, Poison Potion, and AscensionBeat Act 3 with the Silent to reveal this Epoch.
PoisonerUnlocks: Hand Trick, Master Planner, and ReflexKill 15 Elites with the Silent to reveal this Epoch.
Laser BeamsUnlocks: Emotion Chip, Gold-Plated Cables, and Power CellKill 15 Bosses with the Defect to reveal this Epoch.
AblazeUnlocks: Cinder, Drum of Battle, and Pact's EndKill 15 Elites with the Ironclad to reveal this Epoch.
The CalmUnlocks: Powdered Demise, Ship in a Bottle, and Touch of InsanityUnlock by accumulating score.
Bigger PreyUnlocks: Accelerant, Bubble Bubble, and SnakebiteBeat Act 1 with the Silent to reveal this Epoch.
OrobasUnlocked Ancient: Orobas.Play a run with every character to reveal this Epoch.
CultistsUnlocks: Trash HeapUnlock by accumulating score.
AriseUnlocks: Beating Remnant, Joss Paper, and Tiny MailboxUnlock by accumulating score.
DiscontentUnlocks: Mini Regent, Orange Dough, and RegaliteKill 15 Bosses with the Regent to reveal this Epoch.
Hello! Hello!Unlocks: Data Disk, Metronome, and Symbiotic VirusBeat Act 2 with the Defect to reveal this Epoch.
CivilizationUnlocks: Festive Popper, Ripple Basin, and Vexing PuzzleboxUnlock by accumulating score.
Resolving BugsUnlocks: Essence of Darkness, Focus Potion, Potion of Capacity, and AscensionBeat Act 3 with the Defect to reveal this Epoch.
Anomalous PlanetUnlocked the Regent as a playable character.Play a run with the Silent to reveal this Epoch.
IllUnlocks: Paper Krane, Tingsha, and Tough BandagesBeat Act 2 with the Silent to reveal this Epoch.
SnuffedUnlocks: Charon's Ashes, Demon Tongue, and Self-Forming ClayKill 15 Bosses with the Ironclad to reveal this Epoch.
FriendsUnlocks: Arsenal, BEGONE!, and SupermassiveKill 15 Elites with the Regent to reveal this Epoch.
ConfrontationUnlocks: Barrage, Flak Cannon, and SmokestackKill 15 Elites with the Defect to reveal this Epoch.
OpenUnlocks: Beetle Juice, Droplet of Precognition, and Mazaleth's GiftUnlock by accumulating score.
NeowUnlocked the Ancient: Neow.Play a single run to reveal this Epoch.
The TwelveUnlocks: Countdown, Oblivion, and ScourgeBeat Act 1 with the Necrobinder to reveal this Epoch.
Fog Rolls InUnlocked the Silent as a playable character.Play a run with the Ironclad to reveal this Epoch.
I ArriveUnlocks: Furnace, Spoils of Battle, and Sword SageBeat Act 1 with the Regent to reveal this Epoch.
They ReturnUnlocks: Reflections snoitcelfeRUnlock by accumulating score.
Booting UpUnlocked the Defect as a playable character.Play a run with the Necrobinder to reveal this Epoch.
FutilityUnlocks: Bone Flute, Book Repair Knife, and Funerary MaskBeat Act 2 with the Necrobinder to reveal this Epoch.
UnderdocksUnlocked the Underdocks, an alternate Act 1.Unlock by accumulating score.
We Need a Hero!Unlocks: Fencing Manual, Galactic Dust, and Lunar PastryBeat Act 2 with the Regent to reveal this Epoch.
TrickedUnlocks: Consuming Shadow, Loop, and NullBeat Act 1 with the Defect to reveal this Epoch.
SpirebornUnlocks: Bone Brew, Potion of Doom, Pot of Ghouls, and AscensionBeat Act 3 with the Necrobinder to reveal this Epoch.
Grand StrategyUnlocks: Cosmic Concoction, King's Courage, Star Potion, and AscensionBeat Act 3 with the Regent to reveal this Epoch.
The GiantUnlocks: Afterlife, Calcify, and SacrificeKill 15 Elites with the Necrobinder to reveal this Epoch.
AnnihilationUnlocks: Big Hat, Bookmark, and Ivory TileKill 15 Bosses with the Necrobinder to reveal this Epoch.
DarvUnlocked Ancient: Darv.Encounter all other Ancients to reveal this Epoch.
Life and DeathUnlocked the Necrobinder as a playable character.Play a run with the Regent to reveal this Epoch.
Little KingUnlocks: Heavenly Drill, Lunar Blast, and PatterBeat Ascension 1 with the Regent to reveal this Epoch.
My FaceUnlocks: Blood Wall, Inferno, and Tear AsunderBeat Ascension 1 with the Ironclad to reveal this Epoch.
SoupUnlocks: Blade of Ink, Hidden Daggers, and Phantom BladesBeat Ascension 1 with the Silent to reveal this Epoch.
The DailyUnlocked game mode: Daily.Play a single run with all characters and beat Act 3 to reveal this Epoch.
Ooh Shiny!Unlocks: Helix Drill, Scavenge, and TURBOBeat Ascension 1 with the Defect to reveal this Epoch.
To KillUnlocks: Banshee's Cry, Sculpting Strike, and VeilpiercerBeat Ascension 1 with the Necrobinder to reveal this Epoch.