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Slay the Spire 2
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Doom
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Doom
At the end of the enemy turn, if it has at least as much Doom as HP, it dies.
Cards
Blight Strike
Deathbringer
End of Days
Negative Pulse
No Escape
Scourge
In the tooltips of
Potion of Doom
Countdown
Neurosurge
Reaper Form
Shroud
Book Repair Knife
Undying Sigil
Mentioned in
Fairy in a Bottle in Slay the Spire 2: when it saves you and when it cannot
Test Subject in Slay the Spire 2 co-op: health by party size
Necrobinder Doom in Slay the Spire 2: every card that applies or uses Doom
Slay the Spire 2 act 3 bosses: which ones you can meet
Necrobinder guide: Osty, Summon, Souls and Doom in Slay the Spire 2
Slay the Spire 2 update, 18 June 2026: RNG rework, Steam Workshop, Bestiary
Slay the Spire 2 patch, 26 April 2026: card reworks and Neow's Fury buff
Slay the Spire 2 patch, 9 April 2026: daily leaderboards and Not Yet
Slay the Spire 2 patch, 2 April 2026: Badges and Blade of Ink rework
Slay the Spire 2 patch, 26 March 2026: Prepared returns, relic rarity changes
Slay the Spire 2 patch, 19 March 2026: balance pass against infinites